The PLmaddon package was developed as an add-on for the Systems Biology Toolbox 2 for MATLAB. The module offers a set of functions for the analysis of S-system and GMA models, two kinds of power-law models used for mathematical modelling of biochemical systems.
The current version of PLmaddon includes the following features:
- Conversion of models from matrix format to SBtoolbox2 format
- Estimation of steady states of the system in S-System and GMA models
- Local stability analysis
- Estimation of logarithmic gains
- Estimation of sensitivities
- Functions for improved visualization of logarithmic gains and sensitivities
Additional power-law models functions are being implemented for the new version of the module, including:
- Local expansion of other biochemical models as power-law models
- Optimisation with biotechnological purposes
- Analysis of systems with moiety conservation
Since the package is fully integrated in SBToolbox2, the general purposes functions included in this package can also be used for the analysis of power-law models, including conversion to SBML format.
News / History
- Jul/2007 Version 1.1.2 - bugs revised
- May/2007
- GUI of the function pl_estimate was replaced by a Java GUI
- equivalent functions to pl_estimate for text file input: txtSsystem, txtGMAmodel
- APPLICATION NOTE: PLMaddon: a power-law module for the MatlabTM SBToolbox, Bioinformatics Advance Access published on May 11, 2007. doi:10.1093/bioinformatics/btm245
- Dec/2006 new function for PowerLaw expansion included: pl_estimate
- Sep/2006. First release.